Cancer Immunotherapy
Re-Engineered

Turnstone Biologics Inc. is the leading virus-based immunoncology biotechnology company developing novel oncolytic vaccine therapeutics for cancer patients. Our first-in-class platform technology attacks tumours using a two-pronged approach: targeted and robust tumour killing using an oncolytic virus, in combination with a cancer vaccine that generates long-lasting anti-tumour immune responses. Turnstone is building a world-class, high-performing team that embraces being a learning organization with a sense of urgency. Turnstone has a seasoned board of directors and venture capital partners, is enrolling clinical studies, has a rich development portfolio, and highly active R&D efforts led by a world-class scientific management team. Turnstone is co-located in Ottawa, Canada and New York, USA. For more information, please visit www.turnstonebio.com.

Position Overview:

Imagine coming to work every day where over-communication, transparency, teaching, listening, asking, thinking, working hard, and having fun are normal – actually, expected? Imagine having a coach, mentor, peers, and partners where candid feedback, self-improvement, risk taking, failing, learning from that failing, and succeeding are what we call ‘another Thursday at Turnstone’? At Turnstone, the science drives decision making, and our drugs are designed with the patient in mind. Like the disease we’re fighting, our platform is complex, and transformative. If you’re a passionate person, and our science excites you – this opportunity may be for you.

Responsibilities
• Partner with internal and external stakeholders to track orders, prepare documentation and coordinate/monitor the delivery of shipments, globally. Ensure full compliance of import/export operation activities are met based on applicable regulatory requirements.
• Effectively and proactively manage inquiries and any logistics-related issues received from internal and external customers, carrier companies, Customs or other regulatory bodies.
• Monitor expiration of permits and import licenses, and prepare documentation for new applications or renewals, as required.
• Logistics and inventory coordination/traceability – ensure accuracy of transactions to maintain reliable inventory reports.

What’s in it for you?

In this role, you will have the opportunity to develop your ability to think both strategically and drive fast-paced execution. With our company size and growth we will give you plenty of opportunities for you to be an inspirational and collaborative co-functional leader. Passionate about being a part of a critical function of a growing company and continuous learning? We will have plenty of that for you!

We are in the early stages of building strategies, structures and process so this role will be busy and expanding. We also have opportunities for you to be a mentor to other team members. You would have the opportunity to create something new and ‘WOW!’ all of us and grow right along with the company.

Experience & Qualifications:

Requirements:
• BS/BA required (science or business preferred), or equivalent combination of education and experience.
• Requires a minimum of 3-5 years’ experience that includes in-depth understanding of cGMP Logistics operations in the Pharma/Biotech field or relevant field.
• Must have a working knowledge of Trade Compliance responsibilities, on both the import and export sides of the logistics business.
• Cold Chain experience required.
• Working experience and knowledge of applicable regulatory requirements (FDA, CDC, USDA, EU, FAA, IATA, DOT, Customs, and OSHA).
• Experience / ability to understand and develop procedures and other controlled documents required.

To Apply:

Please click here to apply!

Turnstone Biologics welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process. We thank all applicants for their interest, however, only those selected will be invited for an interview.

Turnstone Biologics is a clinical-stage, immuno-oncology company focused on the development of next-generation oncolytic viral immunotherapies for patients with a broad range of solid tumors. Turnstone’s unique, first-in-class oncolytic viral immunotherapies combine the potent tumor-killing effects of an oncolytic virus with a tumor-targeted T-cell vaccine to harness an individual’s own immune system to attack the tumor, preventing recurrence and delivering a cure. Turnstone’s robust pipeline of early-stage compounds, based on its MG1 oncolytic virus platform, are in development for multiple solid tumors and are being evaluated in combination with other cancer immunotherapies, including checkpoint inhibitors, to drive unprecedented, durable T-cell immune responses and strong anti-tumor activity and prevent recurrence. Turnstone is building a world-class, high-performing company that embraces being a learning organization with a sense of urgency. Turnstone has a seasoned board of directors and venture capital partners, is enrolling clinical studies, has a rich development portfolio, and highly active R&D efforts led by a world-class scientific management team. Turnstone is co-located in Ottawa, Hamilton, Canada and New York, USA.

Position Overview:
Imagine coming to work every day where over-communication, transparency, teaching, listening, asking, thinking, working hard, and having fun are normal – actually, expected? Imagine having a coach, mentor, peers, and partners where candid feedback, self-improvement, risk taking, failing, learning from that failing, and succeeding are what we call ‘another day at Turnstone’? At Turnstone, the science drives decision making, and our drugs are designed with the patient in mind. Like the disease we’re fighting, our platform is complex, and transformative. If you’re a passionate person, and our science excites you – this opportunity may be for you.

Our Bioprocess Development and Manufacturing Sciences (PD&MS) team is growing. As part of the Technical Operations organization, the PD&MS team is responsible for leading the overall strategy and technical development for Drug Substance, and Drug Product for our clinical-staged assets. PD&MS also supports technical transfers, and collaborates closely with Manufacturing to provide technical support for GMP operations. As the Senior Manager of Process Development on PD&MS team, you will report to the Director, Bioprocess Development & Manufacturing Sciences. You will be charged with leading a team of Scientists and Engineers to ensure success of our process development workstreams executing within our virtual CDMO network. The responsibilities for this position span across our multi-virus platform and include:

– Providing leadership and guidance to a team of Scientists and Engineers
– Provide technical input for process improvements, with a large focus on upstream process development
– Help to develop the quality Target Product Profile for our viral products
– Represent Turnstone Tech Ops externally at our CDMO network
– Support drafting, and reviewing of regulatory documentation
– Support successful technical transfers and scale-up activities
– Drive corporate and departmental objectives to completion through strong collaboration with a broad range of internal functions, in particular Regulatory Affairs and Quality Assurance

What’s in it for you?
In this role, you will have the opportunity to develop your ability to think both strategically and drive fast-paced execution. With our company size and growth we will give you plenty of opportunities for you to be an inspirational and collaborative co-functional leader. Passionate about being a part of a critical function of a growing company and continuous learning? We will have plenty of that for you!

We are in the early stages of building strategies, structures and process so this role will be busy and expanding. You would have the opportunity to create something new and ‘WOW!’ all of us and grow right along with the company.

Experience & Qualifications:

• The Senior Manager will be positioned in our Ottawa, Canada office Head Quarters
• PhD Biochemical Engineering, or PhD in other related Science field (virology, biology, biochemistry)
• 10+ years experience
• Upstream process development experience including mamammlian cell culture, bioreactor engineering and virus infection/harvest/lysis. Downstrem purification experience considered an asset
• Early stage (clinical development, phase I) process development experience considered an asset
• Broad exposure to different biological drug products. Experience working with viruses considered an asset.
• Experience at a start up biotech strongly preferred
• Strong leadership skills as demonstrated through previous industry roles
• Execllent communication both written, and spoken
• Analytical minded individual with the ability to investigate technically challenging problems
• Mature interpersonal skills and a communication style that matches the Turnstone style: respectful, transparent, and constant
• Excellent computer skills, including Microsoft Excel and Powerpoint
• Able to manage competing priorities effectively and adapt to changing priorities

To Apply:

Please click here to apply!

Turnstone Biologics welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process. We thank all applicants for their interest, however, only those selected will be invited for an interview.

Turnstone Biologics is a clinical-stage, immuno-oncology company focused on the development of next-generation oncolytic viral immunotherapies for patients with a broad range of solid tumors. Turnstone’s unique, first-in-class oncolytic viral immunotherapies combine the potent tumor-killing effects of an oncolytic virus with a tumor-targeted T-cell vaccine to harness an individual’s own immune system to attack the tumor, preventing recurrence and delivering a cure. Turnstone’s robust pipeline of early-stage compounds, based on its MG1 oncolytic virus platform, are in development for multiple solid tumors and are being evaluated in combination with other cancer immunotherapies, including checkpoint inhibitors, to drive unprecedented, durable T-cell immune responses and strong anti-tumor activity and prevent recurrence. Turnstone is building a world-class, high-performing company that embraces being a learning organization with a sense of urgency. Turnstone has a seasoned board of directors and venture capital partners, is enrolling clinical studies, has a rich development portfolio, and highly active R&D efforts led by a world-class scientific management team. Turnstone is co-located in Ottawa, Hamilton, Canada and New York, USA.

Position Overview:

Imagine coming to work every day where over-communication, transparency, teaching, listening, asking, thinking, working hard, and having fun are normal – actually, expected? Imagine having a coach, mentor, peers, and partners where candid feedback, self-improvement, risk taking, failing, learning from that failing, and succeeding are what we call ‘another day at Turnstone’? At Turnstone, the science drives decision making, and our drugs are designed with the patient in mind. Like the disease we’re fighting, our platform is complex, and transformative. If you’re a passionate person, and our science excites you – this opportunity may be for you.

If you are interested in being a part of a growing Technical Operations team, then this role may be for you! As the Director, Quality Assurance, you will oversee the Quality function to ensure GXP compliance in accordance with country regulations and guidelines, as well as the company’s policies and procedures.

The responsibilities include the following:

Drive the development of the company’s Quality strategy and policies.
Oversee company-wide documentation practices, record keeping, training, auditing, raw material qualification and risk assessment, SOPs, batch records, study protocols, reports, investigations, analytical methods, and release specifications.
Lead all QA efforts and documentation for the compliant manufacturing of lead product candidates.
Provide Quality Assurance and compliance oversight for contract manufacturers and research organizations to ensure products/deliverables meet all required quality standards and specifications.
Draft, review, and approve relevant sections of regulatory filings.
Build and scale the QA team to align with business objectives
Represent QA department at project and leadership team meetings.
Drive corporate and department objectives to completion through strong collaboration with a broad range of internal and external functions and levels of management
Cultivate a culture of quality and shared accountability throughout the organization to help ensure compliance with applicable regulations, guidelines, and corporate standards, policies and procedures.
Ensure that the company and its contactors (e.g., CMOs, clinical sites) are prepared for state, regional, or country authority inspections. Coordinate all authority inspections by ensuring sufficient resources are in-place to respond to information requests, adjudicate compliance discussions, and negotiate any required corrective actions.

What’s in it for you?

In this role, you will have the opportunity to develop your ability to think both strategically and drive fast-paced execution. With our company size and growth we will give you plenty of opportunities for you to be an inspirational and collaborative co-functional leader. Passionate about being a part of a critical function of a growing company and continuous learning? We will have plenty of that for you!

We are in the early stages of building strategies, structures and process so this role will be busy and expanding. We also have opportunities for you to be a mentor to other team members. You would have the opportunity to create something new and ‘WOW!’ all of us and grow right along with the company.

Experience & Qualifications:

BA/BS Degree
Minimum of 10 years of operational quality assurance and GxP compliance. Requires manufacturing experience in a pharma or biotech environment, preferably focused in viruses or vaccines, gene or cell therapy.
Prior experience implementing quality systems and advancing novel therapeutics from preclinical stages through IND to BLA is desired.
Effectively managed FDA inspections/audits, and conducted supplier/manufacturer audits.
Demonstrated ability to manage staff and projects (direct and indirectly) and variable workloads with demanding timelines.
Ability to build/scale Quality functions.
Strong interpersonal, teamwork, and organizational skills; effective oral and written communication skills.

To Apply:

Please click here to apply!

Turnstone Biologics welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process. We thank all applicants for their interest, however, only those selected will be invited for an interview.

Turnstone Biologics is a clinical-stage, immuno-oncology company focused on the development of next-generation oncolytic viral immunotherapies for patients with a broad range of solid tumors. Turnstone’s unique, first-in-class oncolytic viral immunotherapies combine the potent tumor-killing effects of an oncolytic virus with a tumor-targeted T-cell vaccine to harness an individual’s own immune system to attack the tumor, preventing recurrence and delivering a cure. Turnstone’s robust pipeline of early-stage compounds, based on its MG1 oncolytic virus platform, are in development for multiple solid tumors and are being evaluated in combination with other cancer immunotherapies, including checkpoint inhibitors, to drive unprecedented, durable T-cell immune responses and strong anti-tumor activity and prevent recurrence. Turnstone is building a world-class, high-performing company that embraces being a learning organization with a sense of urgency. Turnstone has a seasoned board of directors and venture capital partners, is enrolling clinical studies, has a rich development portfolio, and highly active R&D efforts led by a world-class scientific management team. Turnstone is co-located in Ottawa, Hamilton, Canada and New York, USA.

Position Overview:

Imagine coming to work every day where over-communication, transparency, teaching, listening, asking, thinking, working hard, and having fun are normal – actually, expected? Imagine having a coach, mentor, peers, and partners where candid feedback, self-improvement, risk taking, failing, learning from that failing, and succeeding are what we call ‘another Thursday at Turnstone’? At Turnstone, the science drives decision making, and our drugs are designed with the patient in mind. Like the disease we’re fighting, our platform is complex, and transformative. If you’re a passionate person, and our science excites you – this opportunity may be for you.

If you are interested in being the key “go-to” admin person of our Ottawa office, then this role may be for you! Your role will partner closely with most facets of the all the local departments, allowing you to understand the product and process as well as creating our interal administrative system within which we work. You’ll be an integral part of the global admin team, working closely with others in our Ottawa and Hamilton location to ensure the highest quality of consistency and effiency. You will have experience working with some or all the following, as they relate to HR, Executive Admin or Office Management duties:
• Manage the daily operations of the new Ottawa office; including solving administrative problems, addressing human resource issues, and managing supplies within the office
• Support the daily operations of the human resources department including coordinating interviews, hosting candidates, expense reports, offer letters, onboarding, and other duties
• Maintain office organization, professional work environment, and functionality
• Answer incoming telephone calls, greet clients and visitors, and direct them to the conference room or appropriate offices.
• Provide support with daily administrative functions and work on projects to improve efficiencies in the office
• Ensure internal and external guest meetings/ events run efficiently and on time
• Prepare and proactively maintain complex itineraries
• Track travel expenditures and prepare and submit expense reports
• Prepare, coordinate and execute verbal and written communications with meticulous detail and accuracy
• Order office supplies, snacks and drinks for the office and managing inventory levels
• Assist with organization of the annual holiday party
• Manage conference room schedule, including clean up before/after meetings
• Serve as point of contact for building and maintenance staff

What’s in it for you?

In this role, you will have the opportunity to develop this role from scratch. We have not had an HR person yet at Turnstone in Ottawa, we are moving into a brand new space in Q4 2019, we have a lot of new employees…so we are all learning together. Thus, you have the opportunity to create something new and ‘WOW!’ all of us and grow right along with the company.

Experience & Qualifications:

Requirements:
This role is best suited for a some with the following:
• Bachelor’s degree with minimum of 10 years of administrative experience
• Minimum 2+ years HR experience or supporting a HR Executive/Department.
• Prior experience in a support role in biotech/ life sciences industry preferred
• Knowledge of HR processes and procedures/legal compliance.
• Approachable and responsive resource able to connect with employees at all levels
• Ability to manage multiple priorities and consistently meet specific, time sensitive tasks within a fast-paced and small company environment
• Strong internal and external customer service focus, with a genuine desire to assist others
• Strong project management and complex problem-solving skills
• Ability to work effectively with multiple leaders and manage and prioritize multiple priorities and projects with strong attention to detail
• Demonstrated team player while also able to operate independently
• Able to handle sensitive situations and confidential information with professionalism, good judgement and discretion
• Superior business judgment making decisions pertaining to expenses, travel, and priorities
• Proactive, self-motivated and flexible, with an ability to learn and adapt to new systems as they evolve
• Advanced proficiency with Outlook, Excel, PowerPoint, and Word in an Apple/iOS environment

To Apply:

Please click here to apply!

Turnstone Biologics welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process. We thank all applicants for their interest, however, only those selected will be invited for an interview.